BioCapTM MAFA mRNA
Catalog Number: 1002601| SKU | Price | Buy |
|---|---|---|
| 1002601-500ug | $1,550.00 | |
| 1002601-1mg | $2,025.00 |
Ships in ~5 business days
Description
GENE NAME (BOLD) / SYNONYMS:
MAFA
SPECIES:
Human
ENCODED PROTEIN NAME:
Transcription factor MafA
Function:
Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. (Source: UniProt http://www.uniprot.org/uniprot/q8nhw3)
Sequence (353 aa):
MAFA
SPECIES:
Human
ENCODED PROTEIN NAME:
Transcription factor MafA
Function:
Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. (Source: UniProt http://www.uniprot.org/uniprot/q8nhw3)
Sequence (353 aa):
MAAELAMGAE LPSSPLAIEY VNDFDLMKFE VKKEPPEAER FCHRLPPGSL SSTPLSTPCS SVPSSPSFCA PSPGTGGGGG AGGGGGSSQA GGAPGPPSGG PGAVGGTSGK PALEDLYWMS GYQHHLNPEA LNLTPEDAVE ALIGSGHHGA HHGAHHPAAA AAYEAFRGPG FAGGGGADDM GAGHHHGAHH AAHHHHAAHH HHHHHHHHGG AGHGGGAGHH VRLEERFSDD QLVSMSVREL NRQLRGFSKE EVIRLKQKRR TLKNRGYAQS CRFKRVQQRH ILESEKCQLQ SQVEQLKLEV GRLAKERDLY KEKYEKLAGR GGPGSAGGAG FPREPSPPQA GPGGAKGTAD FFL
Gene Coding Sequence:
For the DNA coding sequence that is used as the template to synthesize the MAFA mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.
For the DNA coding sequence that is used as the template to synthesize the MAFA mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.