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REPORTER PROTEINS CELL LINEAGE SPECIFIC FACTORS GROWTH FACTORS GROWTH FACTOR RECEPTORS CYTOKINES CYTOKINE RECEPTORS GENOME INTEGRITY APOPTOSIS INNATE IMMUNITY DEVELOPMENTAL BIOLOGY MISCELLANEOUS

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BioCapTM IGFBP3 mRNA

Catalog Number: 1103501
SKUPriceBuy
1103501-500ug$1,705.00
1103501-1mg$2,227.50
Ships in ~5 business days

Description

GENE NAME (BOLD) / SYNONYMS:

IGFBP3 / IBP3

SPECIES:

Human

ENCODED PROTEIN NAME:

Insulin-like growth factor-binding protein 3

Function:

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. (Source: UniProt http://www.uniprot.org/uniprot/p17936)

Sequence (291 aa):

MQRARPTLWA AALTLLVLLR GPPVARAGAS SAGLGPVVRC EPCDARALAQ CAPPPAVCAE LVREPGCGCC LTCALSEGQP CGIYTERCGS GLRCQPSPDE ARPLQALLDG RGLCVNASAV SRLRAYLLPA PPAPGNASES EEDRSAGSVE SPSVSSTHRV SDPKFHPLHS KIIIIKKGHA KDSQRYKVDY ESQSTDTQNF SSESKRETEY GPCRREMEDT LNHLKFLNVL SPRGVHIPNC DKKGFYKKKQ CRPSKGRKRG FCWCVDKYGQ PLPGYTTKGK EDVHCYSMQS K

Gene Coding Sequence:

For the DNA coding sequence that is used as the template to synthesize the IGFBP3 mRNA mimetic, please contact us at customerservice@pharna.com.

For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.


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