BioCapTM HBEGF mRNA
Catalog Number: 1104301| SKU | Price | Buy |
|---|---|---|
| 1104301-500ug | $1,550.00 | |
| 1104301-1mg | $2,025.00 |
Ships in ~5 business days
Description
GENE NAME (BOLD) / SYNONYMS:
HBEGF / DTR DTS HEGFL
SPECIES:
Human
ENCODED PROTEIN NAME:
Proheparin-binding EGF-like growth factor
Function:
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. (Source: UniProt http://www.uniprot.org/uniprot/q99075)
Sequence (208 aa):
HBEGF / DTR DTS HEGFL
SPECIES:
Human
ENCODED PROTEIN NAME:
Proheparin-binding EGF-like growth factor
Function:
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. (Source: UniProt http://www.uniprot.org/uniprot/q99075)
Sequence (208 aa):
MKLLPSVVLK LFLAAVLSAL VTGESLERLR RGLAAGTSNP DPPTVSTDQL LPLGGGRDRK VRDLQEADLD LLRVTLSSKP QALATPNKEE HGKRKKKGKG LGKKRDPCLR KYKDFCIHGE CKYVKELRAP SCICHPGYHG ERCHGLSLPV ENRLYTYDHT TILAVVAVVL SSVCLLVIVG LLMFRYHRRG GYDVENEEKV KLGMTNSH
Gene Coding Sequence:
For the DNA coding sequence that is used as the template to synthesize the HBEGF mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.
For the DNA coding sequence that is used as the template to synthesize the HBEGF mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.