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REPORTER PROTEINS CELL LINEAGE SPECIFIC FACTORS GROWTH FACTORS GROWTH FACTOR RECEPTORS CYTOKINES CYTOKINE RECEPTORS GENOME INTEGRITY APOPTOSIS INNATE IMMUNITY DEVELOPMENTAL BIOLOGY MISCELLANEOUS

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BioCapTM CCL14 mRNA

Catalog Number: 1301001
SKUPriceBuy
1301001-500ug$1,705.00
1301001-1mg$2,227.50
Ships in ~5 business days

Description

GENE NAME (BOLD) / SYNONYMS:

CCL14 / NCC2 SCYA14

SPECIES:

Human

ENCODED PROTEIN NAME:

C-C motif chemokine 14

Function:

Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induces intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes, eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. (Source: UniProt http://www.uniprot.org/uniprot/q16627)

Sequence (93 aa):

MKISVAAIPF FLLITIALGT KTESSSRGPY HPSECCFTYT TYKIPRQRIM DYYETNSQCS KPGIVFITKR GHSVCTNPSD KWVQDYIKDM KEN

Gene Coding Sequence:

For the DNA coding sequence that is used as the template to synthesize the CCL14 mRNA mimetic, please contact us at customerservice@pharna.com.

For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.


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