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BioCapTM CCL19 mRNA

Catalog Number: 1301501
SKUPriceBuy
1301501-500ug$1,705.00
1301501-1mg$2,227.50
Ships in ~5 business days

Description

GENE NAME (BOLD) / SYNONYMS:

CCL19 / ELC MIP3B SCYA19

SPECIES:

Human

ENCODED PROTEIN NAME:

C-C motif chemokine 19

Function:

May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. (Source: UniProt http://www.uniprot.org/uniprot/q99731)

Sequence (98 aa):

MALLLALSLL VLWTSPAPTL SGTNDAEDCC LSVTQKPIPG YIVRNFHYLL IKDGCRVPAV VFTTLRGRQL CAPPDQPWVE RIIQRLQRTS AKMKRRSS

Gene Coding Sequence:

For the DNA coding sequence that is used as the template to synthesize the CCL19 mRNA mimetic, please contact us at customerservice@pharna.com.

For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.


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