BioCapTM IL1B mRNA
Catalog Number: 1302601| SKU | Price | Buy |
|---|---|---|
| 1302601-500ug | $1,705.00 | |
| 1302601-1mg | $2,227.50 |
Ships in ~5 business days
Description
GENE NAME (BOLD) / SYNONYMS:
IL1B / IL1F2
SPECIES:
Human
ENCODED PROTEIN NAME:
Interleukin-1 beta
Function:
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850). (Source: UniProt http://www.uniprot.org/uniprot/p01584)
Sequence (269 aa):
IL1B / IL1F2
SPECIES:
Human
ENCODED PROTEIN NAME:
Interleukin-1 beta
Function:
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850). (Source: UniProt http://www.uniprot.org/uniprot/p01584)
Sequence (269 aa):
MAEVPELASE MMAYYSGNED DLFFEADGPK QMKCSFQDLD LCPLDGGIQL RISDHHYSKG FRQAASVVVA MDKLRKMLVP CPQTFQENDL STFFPFIFEE EPIFFDTWDN EAYVHDAPVR SLNCTLRDSQ QKSLVMSGPY ELKALHLQGQ DMEQQVVFSM SFVQGEESND KIPVALGLKE KNLYLSCVLK DDKPTLQLES VDPKNYPKKK MEKRFVFNKI EINNKLEFES AQFPNWYIST SQAENMPVFL GGTKGGQDIT DFTMQFVSS
Gene Coding Sequence:
For the DNA coding sequence that is used as the template to synthesize the IL1B mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.
For the DNA coding sequence that is used as the template to synthesize the IL1B mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.