BioCapTM IL18 mRNA
Catalog Number: 1304301| SKU | Price | Buy |
|---|---|---|
| 1304301-500ug | $1,705.00 | |
| 1304301-1mg | $2,227.50 |
Ships in ~5 business days
Description
GENE NAME (BOLD) / SYNONYMS:
IL18 / IGIF IL1F4
SPECIES:
Human
ENCODED PROTEIN NAME:
Interleukin-18
Function:
A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed:14528293, PubMed:25500532). Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed:10653850). (Source: UniProt http://www.uniprot.org/uniprot/q14116)
Sequence (193 aa):
IL18 / IGIF IL1F4
SPECIES:
Human
ENCODED PROTEIN NAME:
Interleukin-18
Function:
A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed:14528293, PubMed:25500532). Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed:10653850). (Source: UniProt http://www.uniprot.org/uniprot/q14116)
Sequence (193 aa):
MAAEPVEDNC INFVAMKFID NTLYFIAEDD ENLESDYFGK LESKLSVIRN LNDQVLFIDQ GNRPLFEDMT DSDCRDNAPR TIFIISMYKD SQPRGMAVTI SVKCEKISTL SCENKIISFK EMNPPDNIKD TKSDIIFFQR SVPGHDNKMQ FESSSYEGYF LACEKERDLF KLILKKEDEL GDRSIMFTVQ NED
Gene Coding Sequence:
For the DNA coding sequence that is used as the template to synthesize the IL18 mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.
For the DNA coding sequence that is used as the template to synthesize the IL18 mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.