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BioCapTM IL26 mRNA

Catalog Number: 1305101
SKUPriceBuy
1305101-500ug$1,705.00
1305101-1mg$2,227.50
Ships in ~5 business days

Description

GENE NAME (BOLD) / SYNONYMS:

IL26 / AK155

SPECIES:

Human

ENCODED PROTEIN NAME:

Interleukin-26

Function:

May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. (Source: UniProt http://www.uniprot.org/uniprot/q9nph9)

Sequence (171 aa):

MLVNFILRCG LLLVTLSLAI AKHKQSSFTK SCYPRGTLSQ AVDALYIKAA WLKATIPEDR IKNIRLLKKK TKKQFMKNCQ FQEQLLSFFM EDVFGQLQLQ GCKKIRFVED FHSLRQKLSH CISCASSARE MKSITRMKRI FYRIGNKGIY KAISELDILL SWIKKLLESS Q

Gene Coding Sequence:

For the DNA coding sequence that is used as the template to synthesize the IL26 mRNA mimetic, please contact us at customerservice@pharna.com.

For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.


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