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BioCapTM CXCR1 mRNA

Catalog Number: 1401301
SKUPriceBuy
1401301-500ug$1,705.00
1401301-1mg$2,227.50
Ships in ~5 business days

Description

GENE NAME (BOLD) / SYNONYMS:

CXCR1 / CMKAR1 IL8RA

SPECIES:

Human

ENCODED PROTEIN NAME:

C-X-C chemokine receptor type 1

Function:

Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. (Source: UniProt http://www.uniprot.org/uniprot/p25024)

Sequence (350 aa):

MSNITDPQMW DFDDLNFTGM PPADEDYSPC MLETETLNKY VVIIAYALVF LLSLLGNSLV MLVILYSRVG RSVTDVYLLN LALADLLFAL TLPIWAASKV NGWIFGTFLC KVVSLLKEVN FYSGILLLAC ISVDRYLAIV HATRTLTQKR HLVKFVCLGC WGLSMNLSLP FFLFRQAYHP NNSSPVCYEV LGNDTAKWRM VLRILPHTFG FIVPLFVMLF CYGFTLRTLF KAHMGQKHRA MRVIFAVVLI FLLCWLPYNL VLLADTLMRT QVIQESCERR NNIGRALDAT EILGFLHSCL NPIIYAFIGQ NFRHGFLKIL AMHGLVSKEF LARHRVTSYT SSSVNVSSNL

Gene Coding Sequence:

For the DNA coding sequence that is used as the template to synthesize the CXCR1 mRNA mimetic, please contact us at customerservice@pharna.com.

For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.


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