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Modified nucleotides: 100% 5-methoxyuridine

Cap type: BioCapTM Cap1

Country of origin: USA

For research use only. Not for use in humans. Not for resale without express written permission of phaRNA. The purchase of any phaRNA product does not grant or imply any license under any patent or patent pending. phaRNA does not warrant that any use or sale of products provided by phaRNA will not infringe the claims of any patents or patents pending in the United States or elsewhere covering the use of the product alone or in combination with other products or in the operation of any process. The purchaser has sole responsibility for all and any use of phaRNA products.



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BioCapTM TNFRSF14 mRNA

Catalog Number: 1405001
SKUPriceBuy
1405001-500ug$1,705.00
1405001-1mg$2,227.50
Ships in ~5 business days

Description

GENE NAME (BOLD) / SYNONYMS:

TNFRSF14 / HVEA HVEM

SPECIES:

Human

ENCODED PROTEIN NAME:

Tumor necrosis factor receptor superfamily member 14

Function:

Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. (Microbial infection) Acts as a receptor for Herpes simplex virus 1/HHV-1. (Microbial infection) Acts as a receptor for Herpes simplex virus 2/HHV-2. (Source: UniProt http://www.uniprot.org/uniprot/q92956)

Sequence (283 aa):

MEPPGDWGPP PWRSTPKTDV LRLVLYLTFL GAPCYAPALP SCKEDEYPVG SECCPKCSPG YRVKEACGEL TGTVCEPCPP GTYIAHLNGL SKCLQCQMCD PAMGLRASRN CSRTENAVCG CSPGHFCIVQ DGDHCAACRA YATSSPGQRV QKGGTESQDT LCQNCPPGTF SPNGTLEECQ HQTKCSWLVT KAGAGTSSSH WVWWFLSGSL VIVIVCSTVG LIICVKRRKP RGDVVKVIVS VQRKRQEAEG EATVIEALQA PPDVTTVAVE ETIPSFTGRS PNH

Gene Coding Sequence:

For the DNA coding sequence that is used as the template to synthesize the TNFRSF14 mRNA mimetic, please contact us at customerservice@pharna.com.

For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.


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