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BioCapTM TNFRSF14 mRNA

Catalog Number: 1405001
SKUPriceBuy
1405001-500ug$1,705.00
1405001-1mg$2,227.50
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Description

GENE NAME (BOLD) / SYNONYMS:

TNFRSF14 / HVEA HVEM

SPECIES:

Human

ENCODED PROTEIN NAME:

Tumor necrosis factor receptor superfamily member 14

Function:

Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. (Microbial infection) Acts as a receptor for Herpes simplex virus 1/HHV-1. (Microbial infection) Acts as a receptor for Herpes simplex virus 2/HHV-2. (Source: UniProt http://www.uniprot.org/uniprot/q92956)

Sequence (283 aa):

MEPPGDWGPP PWRSTPKTDV LRLVLYLTFL GAPCYAPALP SCKEDEYPVG SECCPKCSPG YRVKEACGEL TGTVCEPCPP GTYIAHLNGL SKCLQCQMCD PAMGLRASRN CSRTENAVCG CSPGHFCIVQ DGDHCAACRA YATSSPGQRV QKGGTESQDT LCQNCPPGTF SPNGTLEECQ HQTKCSWLVT KAGAGTSSSH WVWWFLSGSL VIVIVCSTVG LIICVKRRKP RGDVVKVIVS VQRKRQEAEG EATVIEALQA PPDVTTVAVE ETIPSFTGRS PNH

Gene Coding Sequence:

For the DNA coding sequence that is used as the template to synthesize the TNFRSF14 mRNA mimetic, please contact us at customerservice@pharna.com.

For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.


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