BioCapTM BAK1 mRNA
Catalog Number: 1700301| SKU | Price | Buy |
|---|---|---|
| 1700301-500ug | $1,550.00 | |
| 1700301-1mg | $2,025.00 |
Ships in ~5 business days
Description
GENE NAME (BOLD) / SYNONYMS:
BAK1 / BAK BCL2L7 CDN1
SPECIES:
Human
ENCODED PROTEIN NAME:
Bcl-2 homologous antagonist/killer
Function:
Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. (Source: UniProt http://www.uniprot.org/uniprot/q16611)
Sequence (211 aa):
BAK1 / BAK BCL2L7 CDN1
SPECIES:
Human
ENCODED PROTEIN NAME:
Bcl-2 homologous antagonist/killer
Function:
Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. (Source: UniProt http://www.uniprot.org/uniprot/q16611)
Sequence (211 aa):
MASGQGPGPP RQECGEPALP SASEEQVAQD TEEVFRSYVF YRHQQEQEAE GVAAPADPEM VTLPLQPSST MGQVGRQLAI IGDDINRRYD SEFQTMLQHL QPTAENAYEY FTKIATSLFE SGINWGRVVA LLGFGYRLAL HVYQHGLTGF LGQVTRFVVD FMLHHCIARW IAQRGGWVAA LNLGNGPILN VLVVLGVVLL GQFVVRRFFK S
Gene Coding Sequence:
For the DNA coding sequence that is used as the template to synthesize the BAK1 mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.
For the DNA coding sequence that is used as the template to synthesize the BAK1 mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.