BioCapTM BAK1 mRNA
Catalog Number: 1700301| SKU | Price | Buy |
|---|---|---|
| 1700301-500ug | $1,550.00 | |
| 1700301-1mg | $2,025.00 |
Description
BAK1 / BAK BCL2L7 CDN1
SPECIES:
Human
ENCODED PROTEIN NAME:
Bcl-2 homologous antagonist/killer
Function:
Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. (Source: UniProt http://www.uniprot.org/uniprot/q16611)
Sequence (211 aa):
For the DNA coding sequence that is used as the template to synthesize the BAK1 mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.
PhaRNA, LLC is looking for academic and industry collaborators and partners to co-develop RNA-based therapeutics including vaccines for the prevention or treatment of microbial diseases caused by parasites, fungi, viruses and bacteria. Our company’s proprietary technology has the versatility of rapidly designing RNA-based products for testing and development in preclinical and clinical settings. More specifically, we are looking for potential collaborators and partners who have the capacity to take our custom-designed RNA products and test their efficacy using molecular, cell biological and animal models. We will then partner to develop the most promising drug candidates through early phase clinical studies. We believe that this form of collaboration will capitalize on the strengths of PhaRNA, LLC and the partnering organization to rapidly test and develop potentially life-saving drugs and vaccines. Interested parties, please contact us directly.