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BioCapTM BAK1 mRNA

Catalog Number: 1700301
SKUPriceBuy
1700301-500ug$1,705.00
1700301-1mg$2,227.50
Ships in ~5 business days

Description

GENE NAME (BOLD) / SYNONYMS:

BAK1 / BAK BCL2L7 CDN1

SPECIES:

Human

ENCODED PROTEIN NAME:

Bcl-2 homologous antagonist/killer

Function:

Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. (Source: UniProt http://www.uniprot.org/uniprot/q16611)

Sequence (211 aa):

MASGQGPGPP RQECGEPALP SASEEQVAQD TEEVFRSYVF YRHQQEQEAE GVAAPADPEM VTLPLQPSST MGQVGRQLAI IGDDINRRYD SEFQTMLQHL QPTAENAYEY FTKIATSLFE SGINWGRVVA LLGFGYRLAL HVYQHGLTGF LGQVTRFVVD FMLHHCIARW IAQRGGWVAA LNLGNGPILN VLVVLGVVLL GQFVVRRFFK S

Gene Coding Sequence:

For the DNA coding sequence that is used as the template to synthesize the BAK1 mRNA mimetic, please contact us at customerservice@pharna.com.

For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.


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