BioCapTM Hand2 mRNA
Catalog Number: 2001201| SKU | Price | Buy |
|---|---|---|
| 2001201-500ug | $1,705.00 | |
| 2001201-1mg | $2,227.50 |
Ships in ~5 business days
Description
GENE NAME (BOLD) / SYNONYMS:
Hand2 / Dhand Hed Thing2
SPECIES:
Mouse
ENCODED PROTEIN NAME:
Heart- and neural crest derivatives-expressed protein 2
Function:
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. (Source: UniProt http://www.uniprot.org/uniprot/q61039)
Sequence (217 aa):
Hand2 / Dhand Hed Thing2
SPECIES:
Mouse
ENCODED PROTEIN NAME:
Heart- and neural crest derivatives-expressed protein 2
Function:
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. (Source: UniProt http://www.uniprot.org/uniprot/q61039)
Sequence (217 aa):
MSLVGGFPHH PVVHHEGYPF AAAAAAAAAA AASRCSHEEN PYFHGWLIGH PEMSPPDYSM ALSYSPEYAS GAAGLDHSHY GGVPPGAGPP GLGGPRPVKR RGTANRKERR RTQSINSAFA ELRECIPNVP ADTKLSKIKT LRLATSYIAY LMDLLAKDDQ NGEAEAFKAE IKKTDVKEEK RKKELNEILK STVSSNDKKT KGRTGWPQHV WALELKQ
Gene Coding Sequence:
For the DNA coding sequence that is used as the template to synthesize the Hand2 mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.
For the DNA coding sequence that is used as the template to synthesize the Hand2 mRNA mimetic, please contact us at customerservice@pharna.com.
For potential mRNA mimetics encoding splice variants or isoforms of your interest, please contact us at customerservice@pharna.com and it is our promise to fulfill your needs.